Basic Information
VIS ID
TVIS44025061
Fusion event
HTLV-1-NGLY1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
25782148/25740657 (Hg38)
End
25782148/25740657 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3A
Target gene
NGLY1
miRNAs that regulate target gene
hsa-mir-186-5p
Nearest miRNA
hsa-mir-12127/Upstream/75718; hsa-let-7g/Downstream/5421047;
Nearest TSS
ENST00000440867/Upstream/4311; ENST00000460195/Downstream/42215;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/75578, chr3-CpG: 62/Downstream/42188
Upstream sequence
AAATATGAAGGACATATATAGCATAATGATAAAATCTAATAAAGCTTGATGTTGGTCATAGGTATATGATATATTATACTTTGTTCTTGTATTTATGTTT
Downstream sequence
GATGTATTTCAAAATAAaaaactacagaaaaaaaaactacagagaatgtaaaaaggccagaaatatttatgttcctggagggaaaactcaatatttctaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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