Basic Information
VIS ID
TVIS44025086
Fusion event
HTLV-1-BSN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
49634202/49596769 (Hg38)
End
49634202/49596769 (Hg38)
Orient
-
Location type
Intronic
Target gene
BSN
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-18a-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-8485 ; hsa-mir-3912-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-3941 ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-1914-5p ; hsa-mir-4793-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-1286 ; hsa-mir-3619-3p ; hsa-mir-4436b-3p ; hsa-mir-4632-5p ; hsa-mir-591 ; hsa-mir-626 ; hsa-mir-6721-5p ; hsa-mir-6735-5p ; hsa-mir-6876-3p ; hsa-mir-6879-5p ; hsa-mir-7843-5p
Nearest miRNA
hsa-mir-12127/Upstream/322583; hsa-let-7g/Downstream/209368;
Nearest TSS
ENST00000440867/Upstream/42280; ENST00000467456/Downstream/45000;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/41668, chr3-CpG: 110/Downstream/76766
Upstream sequence
agagagggtctcactattttgcccaggatggagtgtagtcttagtcacagacgtgatcatagcacactacagctttgaactcccaacatcaagtgatcat
Downstream sequence
gctgtctcagcctcctaagtagctgggactacaggcctacaccattgcacctggAttgctgaaacttttttttttctttaaatcatgaatgggtgttagc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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