Basic Information
VIS ID
TVIS44025087
Fusion event
HTLV-1-RNF123 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
49753053/49715620 (Hg38)
End
49753053/49715620 (Hg38)
Orient
+
Location type
Exonic
Target gene
RNF123
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-10a-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-12127/Upstream/441434; hsa-let-7g/Downstream/90517;
Nearest TSS
ENST00000440867/Upstream/2093; ENST00000497099/Downstream/2484;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/25713, chr3-CpG: 136/Downstream/2710
Upstream sequence
GCAGAGGCCACTGCAGTGGAGTCCCTGATGATGCCGCCTCCTGTCCCCCTGCAGAGCCCTGCCCTTCCACCCTGCTGCAGCAGCACATGGCGGACCTCCT
Downstream sequence
ACAGCAGGGTCCTGATGTGGCACCCAGCTTCCTCAACAGCGTCCTCAATCAGCTCAACTGGGCCTTCTCTGAATTCATTGGCATGATCCAAGAGGTGGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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