Basic Information
VIS ID
TVIS44025109
Fusion event
HTLV-1-PTPRG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
61694270/61708596 (Hg38)
End
61694270/61708596 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
PTPRG
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-19b-3p ; hsa-mir-342-5p ; hsa-mir-624-5p ; hsa-mir-193b-3p ; hsa-mir-10a-5p ; hsa-mir-19a-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-4671-3p ; hsa-mir-7844-5p ; hsa-mir-218-5p ; hsa-mir-6867-3p ; hsa-mir-4685-3p ; hsa-mir-642a-5p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-6854-3p ; hsa-mir-4282
Nearest miRNA
hsa-let-7g/Upstream/1090726; hsa-mir-12124/Downstream/5516868;
Nearest TSS
ENST00000440867/Upstream/146685; ENST00000468576/Downstream/508987;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/143693, chr3-CpG: 35/Downstream/610243
Upstream sequence
tgtcaccctgactggagtgcagtggcgcaatctgggcaagctgtgccccctgggttcatgccattcttctgcctcagcctcctgagtagctgggactaca
Downstream sequence
ggcgcctgccaccacgcccagctaatttttttgtaattttttagtagagatggggtttcactgtgttagccaggatggtctcgatctcctgacctcatga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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