Basic Information
VIS ID
TVIS44025113
Fusion event
HTLV-1-MAGI1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
66008823/66023148 (Hg38)
End
66008823/66023148 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAGI1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-34a-5p ; hsa-mir-24-3p ; hsa-mir-324-3p
Nearest miRNA
hsa-let-7g/Upstream/5405278; hsa-mir-12124/Downstream/1202316;
Nearest TSS
ENST00000440867/Upstream/115473; ENST00000484768/Downstream/15160;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/473479, chr3-CpG: 158/Downstream/14550
Upstream sequence
TAGGGGACTTCTGGGTGCTCCAAAAGCAGTGACCACAATGAAGGAAGTGGATCGGGGCATACAGTAGTCTAAACTTGAAAACTCTCCTAAGTTGCATCTC
Downstream sequence
ACATCAGAAGTTCTGGATTACATATAGAATATCCTATCTAAAATTTGAATTCCTAGACAGTCTATTGGAATGTTCCATTCTGATATGGAAATGGAGGGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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