Basic Information
VIS ID
TVIS44025142
Fusion event
HTLV-1-PROS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
93650732/93931888 (Hg38)
End
93650732/93931888 (Hg38)
Orient
-
Location type
Intronic
Target gene
PROS1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-494-3p
Nearest miRNA
hsa-let-7g/Upstream/6705611; hsa-mir-12124/Downstream/2428076;
Nearest TSS
ENST00000440867/Upstream/20731; ENST00000478400/Downstream/26866;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/4816931, chr3-CpG: 39/Downstream/41822
Upstream sequence
ACTTTCTACGTGTTTGGTCTCCCATGACTCCCGCTGCCACAGCTCATACTCTGCTCTTGCACAACTGCCATGAGCTGACTTTAATTTTTGTAAAAGAAAT
Downstream sequence
TATGTGGTTGTGCAGTGGATAAGGTCACTATCTTAAATAATTAGCTGTCCTTTACAAAATAAACCCATCCATCTAAGAGAATGGCTTTTGAAGCAGTCTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate