Basic Information
VIS ID
TVIS44025167
Fusion event
HTLV-1-SEC24B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
110377910/109456754 (Hg38)
End
110377910/109456754 (Hg38)
Orient
+
Location type
Intronic
Target gene
SEC24B
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-98-5p ; hsa-mir-30a-5p ; hsa-mir-296-3p ; hsa-mir-186-5p ; hsa-mir-18a-5p ; hsa-mir-16-5p ; hsa-mir-452-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p
Nearest miRNA
hsa-mir-12113/Upstream/8126340; hsa-mir-1243/Downstream/31944;
Nearest TSS
ENST00000502981/Upstream/22937; ENST00000515114/Downstream/103451;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/22312, chr4-CpG: 113/Downstream/102917
Upstream sequence
atgtggctttttcttaagtctgttaatatgttgaatcacattgaatgtatttcaaatggtcagtcagccttgtattcctaatatgaaccccatttggtca
Downstream sequence
taatgtattttactttcaatatattgttgttttctatttgctgaagttttgttCAATGGTAGagctcacagctaagttaaacaaatacttttcctgaaga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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