Basic Information
VIS ID
TVIS44025172
Fusion event
HTLV-1-CAMK2D integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
GRCh37/hg19
Start
114633239/113712083 (Hg38)
End
114633239/113712083 (Hg38)
Orient
+
Location type
Intronic
Target gene
CAMK2D
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-484 ; hsa-let-7a-5p ; hsa-mir-30c-5p ; hsa-mir-185-5p
Nearest miRNA
hsa-mir-12113/Upstream/559721; hsa-mir-1305/Downstream/944676;
Nearest TSS
ENST00000502981/Upstream/194440; ENST00000503557/Downstream/48985;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1005732, chr4-CpG: 86/Downstream/48830
Upstream sequence
GGAGGTCTGGTGAAGGCCCTTGTCTAAACACCTACCCCCACCCACCACTCCAATGAACAAGCCTTAAACTTCCACTTTTAGAAATTCATTCTTTTAGTGT
Downstream sequence
AAGTCATTGAACTTTCTTAAAATCTAAGTATCATTTAGAGATAAAACTCATTATGCATCCTGAGTCACTTATACTTTCAAGTATGTGAATGTATCACCTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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