Basic Information
VIS ID
TVIS44025177
Fusion event
HTLV-1-SYNPO2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
GRCh37/hg19
Start
119964484/119043329 (Hg38)
End
119964484/119043329 (Hg38)
Orient
-
Location type
Intronic
Target gene
SYNPO2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-150-5p ; hsa-mir-144-5p
Nearest miRNA
hsa-mir-12113/Upstream/4386475; hsa-mir-1305/Downstream/6463930;
Nearest TSS
ENST00000502981/Upstream/19858; ENST00000307128/Downstream/92455;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/206673, chr4-CpG: 67/Downstream/169080
Nearest cancer related gene
SYNPO2(TSG, No orient, 0)
Upstream sequence
TACTAAAGGATCTCTCTTTTCCTCTCTTTCTCTCAAATGTGTATTGATGAGGGCCTATCCATTTTAGTCTCCCCAGAAGTTACTTTTTATCTTAGGCTAA
Downstream sequence
GATTACATATCCATAGCAGTTAAGAGGGCTGATGTAGTATTTTAGCTAATTCATAATATTTTTGTAAATTCATCAATGCATTTGCATGAATTAATACTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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