Basic Information
VIS ID
TVIS44025206
Fusion event
HTLV-1-INPP4B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
143538607/142617454 (Hg38)
End
143538607/142617454 (Hg38)
Orient
+
Location type
Intronic
Target gene
INPP4B
miRNAs that regulate target gene
hsa-mir-222-3p ; hsa-mir-181a-5p ; hsa-mir-765
Nearest miRNA
hsa-mir-12113/Upstream/17110147; hsa-mir-1305/Downstream/726006;
Nearest TSS
ENST00000502981/Upstream/51435; ENST00000510377/Downstream/149365;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/980284, chr4-CpG: 111/Downstream/228333
Nearest cancer related gene
INPP4B(TSG, No orient, 0)
Upstream sequence
CATGCATAGCTGATCTGCACCCACCTTCCCTTAGGTCACAGGGATGACAGCTGGAGGCAAAATGCTCAAGGGCAGCAACCATTGCTTGCTGCTCAGAATA
Downstream sequence
TAATCTCCCCTCCCTTCAGCAAGACCAGGACAGCACCAGAGGCAAAAGCTCACGGCTGGAGAGACACCTCTAGCACAATCTTCACACCTAGAGTGGAAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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