Basic Information
VIS ID
TVIS44025218
Fusion event
HTLV-1-SH3D19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
152110048/151188896 (Hg38)
End
152110048/151188896 (Hg38)
Orient
+
Location type
Intronic
Target gene
SH3D19
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-128-3p ; hsa-mir-183-5p ; hsa-let-7c-5p ; hsa-mir-7151-5p ; hsa-mir-3942-3p ; hsa-mir-7977 ; hsa-mir-4437 ; hsa-mir-4284 ; hsa-mir-383-3p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-378a-5p ; hsa-mir-3157-5p ; hsa-mir-1193 ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4485-5p ; hsa-mir-4691-3p ; hsa-mir-2392 ; hsa-mir-6089 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-4696 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-6501-3p ; hsa-mir-451b ; hsa-mir-508-5p ; hsa-mir-4432
Nearest miRNA
hsa-mir-12113/Upstream/3406228; hsa-mir-1305/Downstream/1300431;
Nearest TSS
ENST00000502981/Upstream/13344; ENST00000455694/Downstream/37170;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/88938, chr4-CpG: 81/Downstream/136143
Upstream sequence
atgttgatgtccttaccagtaggacttcagaatgtgatcttacttgaaaatagagtccatacagatgtaattagttaagataaggtcacactggagttgg
Downstream sequence
atgggccccaatccaacataactggtttcttagaagatggccatctgaagagccaaaccaaggtacaccaaagactgctggtcaacctccataagctaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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