Basic Information
VIS ID
TVIS44025232
Fusion event
HTLV-1-FNIP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
159753497/158832345 (Hg38)
End
159753497/158832345 (Hg38)
Orient
+
Location type
Intronic
Target gene
FNIP2
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-450b-5p ; hsa-mir-3680-3p ; hsa-mir-129-5p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-6797-3p ; hsa-mir-6076
Nearest miRNA
hsa-mir-12113/Upstream/6295829; hsa-mir-1305/Downstream/296457;
Nearest TSS
ENST00000502981/Upstream/265; ENST00000505130/Downstream/38014;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/62674, chr4-CpG: 149/Downstream/270290
Upstream sequence
AGTCCAAATTAACAAAGGGGCTTTAAAAGTGGCTACTGTCCTATAAACAGTGAGTGGGAAAAGACCTTTGACTTTATTAGGTGGCCCTAAAGACAAATGG
Downstream sequence
CTGTCTTTATATGTTTTGAGTCTCCATCTGTTACCCAGTCACCAATTTTTAATTTCCTGGGAAATCAAAAATAAAGAACAAAAGGGAAGGGGCTACATTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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