Basic Information
VIS ID
TVIS44025255
Fusion event
HTLV-1-AADAT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q33
Reference genome
GRCh37/hg19
Start
170990823/170069672 (Hg38)
End
170990823/170069672 (Hg38)
Orient
+
Location type
Intronic
Target gene
AADAT
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-12113/Upstream/4683335; hsa-mir-1305/Downstream/1116512;
Nearest TSS
ENST00000502981/Upstream/36641; ENST00000504509/Downstream/18758;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/41915, chr4-CpG: 62/Downstream/20120
Upstream sequence
ACTAGTTTGAACAAGACCATAATGAGGATGGCCAGCAGCACTGAAGGGTGTTCAGAGAGAGAACGCTGATCCTTAGGACCGACAGAAAGAAAAATGATGA
Downstream sequence
GAATGAAGATGAGAAATTAGTCAACATGAAAGACTGACTTCAACATTTACTTTAAAAGTAGCTACAAATGAGAAAGGAAATTTGCTGGCATGCTGATGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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