Basic Information
VIS ID
TVIS44025289
Fusion event
HTLV-1-SEPSECS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
25161076/25159454 (Hg38)
End
25161076/25159454 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
SEPSECS
miRNAs that regulate target gene
hsa-mir-100-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-216a-5p ; hsa-mir-1264 ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-12113/Upstream/639164; hsa-mir-1243/Downstream/3660128;
Nearest TSS
ENST00000502981/Upstream/3356; ENST00000510415/Downstream/940;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/63161, chr4-CpG: 52/Downstream/705
Upstream sequence
ATTTCCGTAAGTGAAACTAACTGAAAACCAATACAACACATCCCCAGTGAAGATGCTTCAAACCAGGGCGTTACGACTGGGGCGGTGGGACGTGGAGAAG
Downstream sequence
GGCGGTAGTTGTCAAACTTCAGTGAAATTTTggccacgcgctgtagctcactcacgcctgtaatccgagcactttggaaggccaagaatggccgatcact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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