Basic Information
VIS ID
TVIS44025295
Fusion event
HTLV-1-STIM2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
26956160/26954538 (Hg38)
End
26956160/26954538 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
STIM2
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-1185-1-3p ; hsa-mir-1185-2-3p
Nearest miRNA
hsa-mir-12113/Upstream/2434248; hsa-mir-1243/Downstream/1865044;
Nearest TSS
ENST00000502981/Upstream/93079; ENST00000477474/Downstream/48462;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/92922, chr4-CpG: 55/Downstream/3323561
Upstream sequence
TGAAGACTCACTTCATTGAATTTCAGATCCTATTTTCAGATTTCTCAATTCATGAATTCCAAATAAGAAGTATTTGTCTTTTGACAAATGAATACAAAGA
Downstream sequence
AGAAGTATTTGTCTTTTGTGTATGCATTTTCAGTTATTGGTGACTGTTTTAAAATTTCTGTAGTTACCCTACTTCATTGCTAAAATGAGGAGGGGTTTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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