Basic Information
VIS ID
TVIS44025327
Fusion event
HTLV-1-FRYL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p11
Reference genome
GRCh37/hg19
Start
48613537/48611520 (Hg38)
End
48613537/48611520 (Hg38)
Orient
+
Location type
Intronic
Target gene
FRYL
miRNAs that regulate target gene
hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-1261 ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-224-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-3171 ; hsa-mir-3681-3p ; hsa-mir-3681-5p ; hsa-mir-376b-5p ; hsa-mir-376c-5p ; hsa-mir-6849-5p
Nearest miRNA
hsa-mir-12113/Upstream/958777; hsa-mir-1243/Downstream/4101162;
Nearest TSS
ENST00000502981/Upstream/5674; ENST00000511662/Downstream/22890;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/119948, chr4-CpG: 121/Downstream/167794
Upstream sequence
atatagaactcacagatatgaaggccctgactgtgtgggtctatttttgagctctccattttgttctatcaatcaatttgtatgtgtctataccaaaatc
Downstream sequence
ataccatctttttaattactaaagcttaataataagttctcatatctagtagtgcaggtcctctccttacttttcttcagagatagcttggctattcttg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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