Basic Information
VIS ID
TVIS44025348
Fusion event
HTLV-1-C4orf50 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
5974658/5972931 (Hg38)
End
5974658/5972931 (Hg38)
Orient
-
Location type
Intronic
Target gene
C4orf50
miRNAs that regulate target gene
hsa-mir-192-3p ; hsa-mir-4312 ; hsa-mir-489-3p ; hsa-mir-4317
Nearest miRNA
hsa-mir-378d-1/Upstream/49603; hsa-mir-12113/Downstream/1337519;
Nearest TSS
ENST00000502981/Upstream/79873; ENST00000507424/Downstream/16716;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/79542, chr4-CpG: 54/Downstream/35210
Nearby gene
MIR378D1(-49603) ;
Upstream sequence
TGCATGTATATGTGTGggcaggcacggctgggcacccgtgggtgctgactgtagtcaggagagctggcatttgtccctgtgtgcactgcctgtgtgaccc
Downstream sequence
ggagcacatctcctaacctctctggcctcagcttcctcttctgtTGACCACTGGGAGAGGAGATTCTCATTCATTTGGTTCATTATttcattcattcaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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