Basic Information
VIS ID
TVIS44025377
Fusion event
HTLV-1-RASGEF1B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
82391049/81469895 (Hg38)
End
82391049/81469895 (Hg38)
Orient
+
Location type
Intronic
Target gene
RASGEF1B
miRNAs that regulate target gene
hsa-mir-195-5p ; hsa-mir-4668-5p ; hsa-mir-1287-3p ; hsa-mir-6868-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-6507-3p
Nearest miRNA
hsa-mir-12113/Upstream/4894269; hsa-mir-1243/Downstream/1283442;
Nearest TSS
ENST00000502981/Upstream/12293; ENST00000609552/Downstream/1341;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/254514, chr4-CpG: 89/Downstream/1561
Upstream sequence
TCAGATAAAATATCCAGTGGAGCACATAAAATGAAGCAAGACTGAAAATGCACCATAGGAGAAATAAATTCTAAGAATGTAACACTTCGTTAGACAACTG
Downstream sequence
GAAAGTACAAGGCCAATATGCTTAGTAGTTAGAAATGTTGCCCACCTCCAAGAAAACAAAGGATTGACCCGACATGCAGTGGAAGAATGCCAACAAGAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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