Basic Information
VIS ID
TVIS44025397
Fusion event
HTLV-1-ST8SIA4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
100212739/100877035 (Hg38)
End
100212739/100877035 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
ST8SIA4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-8485 ; hsa-mir-135a-5p ; hsa-mir-3140-3p ; hsa-mir-4776-3p ; hsa-mir-487b-5p ; hsa-mir-487a-5p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-664a-3p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-181c-5p
Nearest miRNA
hsa-mir-10397/Upstream/60470; hsa-mir-103a-1/Downstream/9636794;
Nearest TSS
ENST00000502646/Upstream/219065; ENST00000506058/Downstream/13847;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/341019, chr5-CpG: 32/Downstream/23828
Upstream sequence
AAGCATTATTTAACGTAATTGATTAATGAATGATACAAACAGCCACTAAGAGAGTACCTTGGTTTATAAAGTTAGAGGTCAACTTGAGTATAATACTTGG
Downstream sequence
GTAAATCTTATCCTTAAGGAGTTACTGTACTAATTAGTGCCCACTGCAAGTAAACCAGGTATAATTTATCTCTCCCTCTCTCTCTCAACAAATTTACTGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate