Basic Information
VIS ID
TVIS44025415
Fusion event
HTLV-1-TNFAIP8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
118699461/119363766 (Hg38)
End
118699461/119363766 (Hg38)
Orient
-
Location type
Intronic
Target gene
TNFAIP8
miRNAs that regulate target gene
hsa-mir-452-5p ; hsa-mir-574-5p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-630 ; hsa-mir-4717-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-92a-2-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6787-3p ; hsa-mir-6884-3p ; hsa-mir-3614-3p ; hsa-mir-9-5p ; hsa-mir-193b-5p ; hsa-mir-483-5p
Nearest miRNA
hsa-mir-10397/Upstream/209050; hsa-mir-103a-1/Downstream/9733922;
Nearest TSS
ENST00000502646/Upstream/7731; ENST00000508750/Downstream/88677;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/7702, chr5-CpG: 33/Downstream/88664
Upstream sequence
gagggtctttcttacaccaaccagttttccaaatttcagcggacgttgactagacgtcctataatttaactcatttctgacactaattgtccagagttag
Downstream sequence
ggcagaccccacaggttaagggctcagtcccacaagactgtcctccaacttgagacagcaattgcaaggccaggcatcccatacttttgaccaactgggt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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