Basic Information
VIS ID
TVIS44025425
Fusion event
HTLV-1-MEIKIN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
131145488/131809795 (Hg38)
End
131145488/131809795 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5C
Target gene
MEIKIN
Nearest miRNA
hsa-mir-10397/Upstream/2412648; hsa-mir-103a-1/Downstream/408054;
Nearest TSS
ENST00000502646/Upstream/12732; ENST00000446275/Downstream/69225;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/12185, chr5-CpG: 44/Downstream/135419
Upstream sequence
ctcgggaggctgaggcaggagaatcgcctgaaccagggagtcggaggttgcagtgagctgccactgcactccagcctggcaacagagtgagactctgtct
Downstream sequence
caaaaaacaagcaaacaaacgaacaaaaaaaaaaaaACAAACAAAACCAAAGAACAGTTTTCAAAAGGGAGATGAAGAAAGCTAAACTTGAGAAATTAAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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