Basic Information
VIS ID
TVIS44025427
Fusion event
HTLV-1-CLPTM1L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1322655/1322540 (Hg38)
End
1322655/1322540 (Hg38)
Orient
+
Location type
Intronic
Target gene
CLPTM1L
miRNAs that regulate target gene
hsa-mir-22-3p ; hsa-mir-5093 ; hsa-mir-203a-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-3688-3p ; hsa-mir-4694-3p ; hsa-mir-6856-3p
Nearest miRNA
hsa-mir-4457/Upstream/13163; hsa-mir-10397/Downstream/188222;
Nearest TSS
ENST00000502646/Upstream/711; ENST00000605200/Downstream/375;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/26685, chr5-CpG: 18/Downstream/12422
Upstream sequence
CTGGTGCTTCCATTTGCTCTAAGGAACCAGACGTGGATGGTGTTGTTTTAATGCTTAGGTTTCCTTGTTTCCATGAAGAAAACAGACAACAGTCATGCAC
Downstream sequence
CACACAATGCTGTTTTCATCAGCGATGGACACATATACCAGGCGGCTGCACCACACAGCCTGGCGTGGAGGGGCTGCCACATCTGGTGTGAGCACTCCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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