Basic Information
VIS ID
TVIS44025451
Fusion event
HTLV-1-PPP2R2B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37/hg19
Start
146313175/146933612 (Hg38)
End
146313175/146933612 (Hg38)
Orient
-
Location type
Intronic
Target gene
PPP2R2B
miRNAs that regulate target gene
hsa-mir-30e-3p ; hsa-mir-6825-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-765 ; hsa-mir-6804-5p ; hsa-mir-665 ; hsa-mir-4779 ; hsa-mir-4459 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-10397/Upstream/3253641; hsa-mir-103a-1/Downstream/2128701;
Nearest TSS
ENST00000502646/Upstream/11036; ENST00000503975/Downstream/122319;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/54600, chr5-CpG: 32/Downstream/301108
Upstream sequence
AACCTATTATCAACCACACTTGGGATACCATTAAGGGCCACCTCACTTTATTCTGAAATTTCTACTTCAGGGAGATTACCAAGCTTCCAGAGAGAAGCAA
Downstream sequence
AATGAGACCCATTTAAGAACATGTGACCTATCGTGACAAACGGAAGTTCTTTTTTTTTTTTAAGTTTTTtttttcttttattattatactttaagtttta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate