Basic Information
VIS ID
TVIS44025452
Fusion event
HTLV-1-ANKH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
14730255/14730146 (Hg38)
End
14730255/14730146 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANKH
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-92a-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-4325 ; hsa-mir-3924 ; hsa-mir-3668 ; hsa-mir-7852-3p ; hsa-mir-1264 ; hsa-mir-4796-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p
Nearest miRNA
hsa-mir-10397/Upstream/4252001; hsa-mir-103a-1/Downstream/95783;
Nearest TSS
ENST00000502646/Upstream/13058; ENST00000607026/Downstream/19081;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/65040, chr5-CpG: 21/Downstream/141136
Upstream sequence
CAGCCCGCTGTGCTGTGATCCATGCTGGGTTCTACAGAAACAGCACGCAAGGTGGGGACCTGACCATGCTGGGTTCTACAGAAACAGCACACAAGGAGGG
Downstream sequence
GACCTGACCAGGCCGCTAAGCCCCTCTCCTCTCTGGCAGCCTCCAACCTAATCCCTTCTCCCGGACAAAGTTTCTCCCCAGAAGCTGGAGCAGGGGGGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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