Basic Information
VIS ID
TVIS44025459
Fusion event
HTLV-1-ANXA6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
150519717/151140156 (Hg38)
End
150519717/151140156 (Hg38)
Orient
+
Location type
Exonic
Target gene
ANXA6
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-877-3p ; hsa-mir-324-5p ; hsa-mir-3138 ; hsa-mir-3689d ; hsa-mir-4520-3p ; hsa-mir-6134 ; hsa-mir-6851-5p ; hsa-mir-7847-3p ; hsa-mir-8071 ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-3191-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-4487 ; hsa-mir-4633-3p ; hsa-mir-484 ; hsa-mir-516b-5p ; hsa-mir-518c-5p ; hsa-mir-593-3p ; hsa-mir-6500-5p ; hsa-mir-6764-3p ; hsa-mir-6824-3p ; hsa-mir-6874-5p
Nearest miRNA
hsa-mir-10397/Upstream/1407266; hsa-mir-103a-1/Downstream/381931;
Nearest TSS
ENST00000502646/Upstream/6833; ENST00000523466/Downstream/1484;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/58853, chr5-CpG: 40/Downstream/17374
Upstream sequence
CCATTTCACAGACCCTACCACCACCACCAGAAGGGCTCTGGGCTGTGTCTACTTTTGGGGGATACCCCTCAAGCTCCCATGAAGCCTGGCACCCACCAAA
Downstream sequence
GCCCTTCATGGCAGTGTACAGAGCCTCGGCATCCTGGTTGGGGTCAAAGCCTGGGAAGTCATGGATGGAGCCCCGGTACTTGGCACCCTGTGGAGAAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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