Basic Information
VIS ID
TVIS44025472
Fusion event
HTLV-1-CYFIP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
156785788/157358780 (Hg38)
End
156785788/157358780 (Hg38)
Orient
-
Location type
Intronic
Target gene
CYFIP2
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-149-5p ; hsa-mir-9-5p ; hsa-mir-3146 ; hsa-mir-335-3p ; hsa-mir-4729 ; hsa-mir-491-3p ; hsa-mir-5003-3p ; hsa-mir-5696 ; hsa-mir-579-3p ; hsa-mir-664b-3p
Nearest miRNA
hsa-mir-10397/Upstream/2529240; hsa-mir-103a-1/Downstream/3115622;
Nearest TSS
ENST00000502646/Upstream/13059; ENST00000522892/Downstream/2625;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/92041, chr5-CpG: 50/Downstream/101181
Upstream sequence
CCATGGCTCAATTTGTAAAACTCCTGGTTTGGGTGTGGAACGTCATGGGTGGCAGGAATCCCTGTAAAAGGGGTATTTGCTTGGAAGCCCTTTATCCTCT
Downstream sequence
TCTGCTAGGGAGTGGCTGCTCCATCTGGTGACTGTGCGCCATCCTGTAGTCACTGACCACACCTCTCTCTATGACCACCATTTTGCAAACATATTCATGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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