Basic Information
VIS ID
TVIS44025513
Fusion event
HTLV-1-CDH18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
19856996/19856887 (Hg38)
End
19856996/19856887 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5E
Target gene
CDH18
miRNAs that regulate target gene
hsa-let-7e-5p
Nearest miRNA
hsa-mir-10397/Upstream/2700895; hsa-mir-103a-1/Downstream/12079215;
Nearest TSS
ENST00000502646/Upstream/17643; ENST00000513573/Downstream/29385;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2201273, chr5-CpG: 45/Downstream/448566
Upstream sequence
ttcaagcactgcgagaaaataaatttctgttgtttcggccacccactctttggtatttgttatggcagccctagcaaatgaacacaCTCACTGACTCGAT
Downstream sequence
TTTTTTTTCTTTCTAAAAGTAATAAAATAGTTCCAAATTAGAAACTTGAGGCAggttgggcaagatcactcacgattgtaatcccaacactttggaaggc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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