Basic Information
VIS ID
TVIS44025531
Fusion event
HTLV-1-AHRR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
339806/339691 (Hg38)
End
339806/339691 (Hg38)
Orient
+
Location type
Intronic
Target gene
AHRR
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26a-5p ; hsa-mir-18a-5p ; hsa-mir-125b-5p
Nearest miRNA
hsa-mir-10397/Downstream/723205;
Nearest TSS
ENST00000502646/Upstream/17051; ENST00000504625/Downstream/3837;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/16796, chr5-CpG: 98/Downstream/3643
Nearest cancer related gene
AHRR(TSG, No orient, 0)
Upstream sequence
acaccacagctttgccttgttcatggtcttggggggaagcatttagtctttcaccattagctgtgatgttagctataggcttttgtagatgttctttatc
Downstream sequence
acgttaattaagtttccttctgttcctagtttgatgagaggtttttttggaaaaattgttatgaatggatttggattttgtcaaatgcttttctgaaaga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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