Basic Information
VIS ID
TVIS44025532
Fusion event
HTLV-1-RAI14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
34677892/34677787 (Hg38)
End
34677892/34677787 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
RAI14
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-122-5p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-423-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10397/Upstream/2283312; hsa-mir-103a-1/Downstream/1470105;
Nearest TSS
ENST00000502646/Upstream/20537; ENST00000510386/Downstream/6720;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/20562, chr5-CpG: 69/Downstream/161029
Upstream sequence
cttggcctcccaaagtgctgggattataggcatgagtcactgcacccagcctctgacttttctgattattcttagatttttaaaaaaagttctgcagtca
Downstream sequence
gtttcaactgctaaatactcttaattcagaatttagagtcctcaatgttggtgaaaaagtaatcgtggtttttgttattttaatggcaaaaactgcaatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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