Basic Information
VIS ID
TVIS44025544
Fusion event
HTLV-1-C6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
41245498/41245396 (Hg38)
End
41245498/41245396 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
C6
miRNAs that regulate target gene
hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-4291 ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-5196-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-6800-5p ; hsa-mir-4539 ; hsa-mir-6865-3p ; hsa-mir-3200-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485
Nearest miRNA
hsa-mir-10397/Upstream/2687835; hsa-mir-103a-1/Downstream/12706108;
Nearest TSS
ENST00000502646/Upstream/31801; ENST00000505931/Downstream/16042;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/409625, chr5-CpG: 26/Downstream/264285
Upstream sequence
agatgggcagatcacctgaggtcaggagttagtgactagcctgactaacatggtgaaaccccatctctatgaaaaattagctgggcgtggtggcagacac
Downstream sequence
ctgtaatcccagctacttcggaggctgaggcaggagaatcgcttgaactcatgggtggagattgcagtgaactgagatagcaccattgcactccagcctg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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