Basic Information
VIS ID
TVIS44025565
Fusion event
HTLV-1-ESM1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
54275970/54980142 (Hg38)
End
54275970/54980142 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5H
Target gene
ESM1
miRNAs that regulate target gene
hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-942-5p ; hsa-mir-532-3p ; hsa-mir-6887-3p ; hsa-mir-1224-3p ; hsa-mir-4640-3p
Nearest miRNA
hsa-mir-10397/Upstream/1028543; hsa-mir-103a-1/Downstream/190390;
Nearest TSS
ENST00000502646/Upstream/22296; ENST00000512089/Downstream/5451;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/95799, chr5-CpG: 47/Downstream/192813
Upstream sequence
acattctgatgtggaatgctttaagaagattagcgtggcccagcagacgaatgtgtgtaagtccatgaaacattccagatcttACTCCCCCAAGACCCTC
Downstream sequence
GTACACAAAAACTTACTTGTGAATTCCCAACTTGGGAAGCTCACTGCCAAAAAAAAGAACACCAAGTGGAACACTGTGGACAGGAAGCACATTTGACAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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