Basic Information
VIS ID
TVIS44025621
Fusion event
HTLV-1-PDSS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
107747903/107426699 (Hg38)
End
107747903/107426699 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6F
Target gene
PDSS2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-142-3p
Nearest miRNA
hsa-mir-10398/Upstream/642479; hsa-mir-1202/Downstream/11642348;
Nearest TSS
ENST00000381078/Upstream/214540; ENST00000618129/Downstream/32864;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/310593, chr6-CpG: 19/Downstream/32332
Nearest cancer related gene
PDSS2(TSG, No orient, 0)
Upstream sequence
ctcaacaccagcccatgaaagcagccaagagggtggctgtaccctgcaaagccacaggggcagagctgcccaagaccatgggagcccaccctttgcatca
Downstream sequence
gcgtgacctgaatgcaagacatggagtcaaaggagattattttggagttttacgatatgactgccctgcttgattttggacttgcatgaggcctgtagcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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