Basic Information
VIS ID
TVIS44025636
Fusion event
HTLV-1-NKAIN2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
124834712/124513566 (Hg38)
End
124834712/124513566 (Hg38)
Orient
+
Location type
Intronic
Target gene
NKAIN2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10398/Upstream/4498309; hsa-mir-1202/Downstream/1971065;
Nearest TSS
ENST00000381078/Upstream/230562; ENST00000640160/Downstream/304833;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/709402, chr6-CpG: 128/Downstream/448412
Upstream sequence
CTTTTAACTCTTCTATTTAGCCCTTGGTAGGGATACTCTTTTTCTTCTGTTTGAAGTAATGGTCTTGTCCAAGACCATTCCAATGTAAGCAGCAGTGTCA
Downstream sequence
TACTATGTGGGTTATAGCATCAAGAACCATGCTTATCAATAGATAGATTTGGGCAAACCATATTGTACCCCCACCTCCAATGGTTTTGGTGGGTTAAATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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