Basic Information
VIS ID
TVIS44025644
Fusion event
HTLV-1-GFOD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p23
Reference genome
GRCh37/hg19
Start
13423668/13423436 (Hg38)
End
13423668/13423436 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6A
Target gene
GFOD1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-9-5p ; hsa-mir-215-5p ; hsa-mir-26b-5p ; hsa-mir-24-3p ; hsa-mir-19b-3p ; hsa-mir-1276 ; hsa-mir-484 ; hsa-mir-100-5p
Nearest miRNA
hsa-mir-3691/Upstream/2983642; hsa-mir-10398/Downstream/2718120;
Nearest TSS
ENST00000381078/Upstream/15299; ENST00000446001/Downstream/48608;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/57719, chr6-CpG: 223/Downstream/62656
Upstream sequence
ttaggtcaaggagcatttATCTGTGTAATATGCCTGACACCATACCTGACACACAGGAAGCAACGTATAAATACCCAAACTCCTCACCCCAGCATTGAGG
Downstream sequence
CCAGATTCCCAATGACAGATGAAACTCATGCACCATGACACACACACAGACACGCCTGAAATATATGATAGTTGGTCTGTTCATTGAGGACCTGTCATGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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