Basic Information
VIS ID
TVIS44025647
Fusion event
HTLV-1-NHSL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
139007183/138686046 (Hg38)
End
139007183/138686046 (Hg38)
Orient
-
Location type
Intronic
Target gene
NHSL1
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-221-3p ; hsa-mir-192-5p ; hsa-mir-32-5p ; hsa-mir-877-3p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-218-5p ; hsa-mir-3613-5p ; hsa-mir-548g-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p
Nearest miRNA
hsa-mir-10398/Upstream/250752; hsa-mir-1202/Downstream/1519206;
Nearest TSS
ENST00000381078/Upstream/113506; ENST00000428044/Downstream/6502;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/261590, chr6-CpG: 156/Downstream/6192
Nearby gene
FLJ46906(+5622) ;
Upstream sequence
cacttcatatagtattatcaaatagtcaaaatgaaactcatagaagcagagagtacaatgatggttaccaagggctgtaggaagaaggtattggagagat
Downstream sequence
attggtcaaaagatacaaaatttctgttaagaggaataagttcaagagatctataatcaacatggtgaccatagctaataacatgtattgcatacttgta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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