Basic Information
VIS ID
TVIS44025654
Fusion event
HTLV-1-AIG1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
143456308/143135171 (Hg38)
End
143456308/143135171 (Hg38)
Orient
-
Location type
Intronic
Target gene
AIG1
miRNAs that regulate target gene
hsa-mir-15b-5p ; hsa-mir-218-5p ; hsa-mir-3656 ; hsa-mir-3974 ; hsa-mir-340-3p ; hsa-mir-4293 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-4531 ; hsa-mir-4786-5p ; hsa-mir-4802-3p ; hsa-mir-5703 ; hsa-mir-6827-3p ; hsa-mir-6849-3p ; hsa-mir-769-5p
Nearest miRNA
hsa-mir-10398/Upstream/2451288; hsa-mir-1202/Downstream/7967504;
Nearest TSS
ENST00000381078/Upstream/8921; ENST00000470265/Downstream/29773;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/73923, chr6-CpG: 40/Downstream/315302
Upstream sequence
ctaccataagctttctggttgttctacatctttgtaacacttggtattgtaagaattaaattgtaaataattacactggtgagaaatgctacctcattgt
Downstream sequence
ggtcttagtttgcatttccctggttgttagttacctttttatgtttactagccaGATTAGCTAGTAATGAAGAATAATGAAGATTATTCTCCTCTGGTAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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