Basic Information
VIS ID
TVIS44025670
Fusion event
HTLV-1-ZDHHC14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
157875559/157454527 (Hg38)
End
157875559/157454527 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZDHHC14
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-130b-3p ; hsa-mir-587 ; hsa-mir-5581-3p ; hsa-mir-3140-3p ; hsa-mir-6872-3p ; hsa-mir-302f ; hsa-mir-451a ; hsa-mir-6511b-5p ; hsa-mir-676-5p ; hsa-mir-6811-5p
Nearest miRNA
hsa-mir-10398/Upstream/674796; hsa-mir-1913/Downstream/74605;
Nearest TSS
ENST00000381078/Upstream/73394; ENST00000523468/Downstream/88058;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/72182, chr6-CpG: 29/Downstream/138253
Upstream sequence
ATCCCTAAGAAAAAGAAGAAAAATGCAACATAACATTACTGATTTTAAAATGCTTTTAATGCAGCTTCTtcttttttttttttttttttgccacgagtct
Downstream sequence
caccctgtttcccaggctagagttcagtggtggtgtgatcctagctcactgcagccttgaactccttggctcaagtgattctcccaccgcctcagcctcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate