Basic Information
VIS ID
TVIS44025672
Fusion event
HTLV-1-TULP4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
158903287/158482255 (Hg38)
End
158903287/158482255 (Hg38)
Orient
-
Location type
Intronic
Target gene
TULP4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-186-5p ; hsa-mir-32-5p ; hsa-mir-484 ; hsa-mir-28-5p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-3688-3p ; hsa-mir-4694-3p ; hsa-mir-4261 ; hsa-mir-578 ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-6881-3p ; hsa-mir-877-3p ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-134-5p ; hsa-mir-197-3p ; hsa-mir-3118 ; hsa-mir-6080 ; hsa-mir-6773-3p ; hsa-mir-6879-3p ; hsa-mir-943
Nearest miRNA
hsa-mir-10398/Upstream/953055; hsa-mir-1913/Downstream/127452;
Nearest TSS
ENST00000381078/Upstream/20605; ENST00000367090/Downstream/54181;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/249217, chr6-CpG: 28/Downstream/33998
Upstream sequence
CTCTCGCCACTTCCTCGCTCCAGTTTACTCTCCTGCCCATTAGTCTGGTCCCTGCCTCTCATTACGACCTGGAGCTAGCATGACCTGTGGCCTGACCAGT
Downstream sequence
CACCCCAAGTCACAGTGTGGTGGGCTTGCTCACTCTCAACTTGTACTCAGCGCTGTACACAGGTGCCCCACCTCTGCCTGCCAGCCTTCATTTGTTCAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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