Basic Information
VIS ID
TVIS44025701
Fusion event
HTLV-1-LTA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
31541880/31574103 (Hg38)
End
31541880/31574103 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA6H
Target gene
LTA
miRNAs that regulate target gene
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-3143/Upstream/218787; hsa-mir-10398/Downstream/59684;
Nearest TSS
ENST00000381078/Upstream/1809; ENST00000449264/Downstream/1464;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/31984, chr6-CpG: 80/Downstream/6556
Upstream sequence
CAGGCACATGGAGGAGCTTGGGGGATGACTAGAGGCAGGGAGGGGACTATTTATGAAGGCaaaaaaattaaattatttatttatGGAGGATGGAGAGAGG
Downstream sequence
GGAATAATAGAAGAACATCCAAGGAGAAACAGAGACAGGCCCAAGAGATGAAGAGTGAGAGGGCATGCGCACAAGGCTGACCAAGAGAGAAAGAAGTAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate