Basic Information
VIS ID
TVIS44025714
Fusion event
HTLV-1-PI16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
36925958/36958182 (Hg38)
End
36925958/36958182 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
PI16
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-1236/Upstream/335670; hsa-mir-10398/Downstream/597183;
Nearest TSS
ENST00000381078/Upstream/3749; ENST00000491324/Downstream/4808;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/72031, chr6-CpG: 35/Downstream/970
Upstream sequence
AGGCAGCGGCTCCTGAAAGCCTTGAGTGGGTGGGGAGTAGGTGTGGCCACACAGCCACCTCCCCTCAGGGTCACCCAAGCTCTTGGCGCTTTATGGGCTG
Downstream sequence
TCTGGCTCCCAGAGCTGGCTGGGCCCTCATAGGGTGGAGCAAGAGCTGCCGCCAGGCCATGGATTTCCAGGAGAAGCCAAGGACAGCGTTTAATGGGATC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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