Basic Information
VIS ID
TVIS44025769
Fusion event
HTLV-1-COL19A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
70614601/69904709 (Hg38)
End
70614601/69904709 (Hg38)
Orient
-
Location type
Intronic
Target gene
COL19A1
miRNAs that regulate target gene
hsa-mir-223-5p ; hsa-mir-126-5p ; hsa-mir-4795-3p ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-496 ; hsa-mir-5571-5p ; hsa-mir-544a ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-3182 ; hsa-mir-676-5p ; hsa-mir-20a-3p ; hsa-mir-6515-3p ; hsa-mir-877-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-330-3p ; hsa-mir-141-5p ; hsa-mir-578 ; hsa-mir-8070 ; hsa-mir-3161 ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-581
Nearest miRNA
hsa-mir-10398/Upstream/12514497; hsa-mir-10524/Downstream/1472251;
Nearest TSS
ENST00000381078/Upstream/37160; ENST00000483745/Downstream/32163;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/37029, chr6-CpG: 61/Downstream/377628
Upstream sequence
atcagatggtcatgttgtaccttttgacagatcatagggtgagcctgcagtggtggagccccctcctcctcaggatcagaccaaatgggactgtccagcc
Downstream sequence
tggaggacaggctcaaggtcaaacttacagctgttgctaactcttgttccaggctgtttatctgggcctccaagtgccctgcttgcacctgaaggtccct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate