Basic Information
VIS ID
TVIS44025781
Fusion event
HTLV-1-TTK integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
80723250/80013533 (Hg38)
End
80723250/80013533 (Hg38)
Orient
+
Location type
Intronic
Target gene
TTK
miRNAs that regulate target gene
hsa-mir-376a-5p ; hsa-mir-376a-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-524-5p
Nearest miRNA
hsa-mir-10398/Upstream/1474224; hsa-mir-1202/Downstream/10299209;
Nearest TSS
ENST00000381078/Upstream/78; ENST00000504590/Downstream/24020;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/8682, chr6-CpG: 53/Downstream/92869
Upstream sequence
CTTTTTCTGGGGAAAGGGTTTATAAATAGTTCATGTATCTCCAACAGTGTTCCACATACCCCAAGAGCTGTGGGACTACGAGTGGGAAGTTGGTGCAGAA
Downstream sequence
GTCCTAGACTATGTTTCTCCAAGATTAAGGTGGTAGAGCAAGGATCAACAATCTTTTAAGAGAATCATGAAGTAATATTTATTATGCACGTGTTTAAGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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