Basic Information
VIS ID
TVIS44025828
Fusion event
HTLV-1-TMEM209 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
129807041/130167201 (Hg38)
End
129807041/130167201 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMEM209
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-99a-5p ; hsa-mir-6807-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-921 ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-661 ; hsa-mir-298 ; hsa-mir-1827 ; hsa-mir-610 ; hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-3192-5p ; hsa-mir-3174 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-382-5p ; hsa-mir-3156-5p
Nearest miRNA
hsa-mir-10525/Upstream/392187; hsa-mir-10399/Downstream/328910;
Nearest TSS
ENST00000635602/Upstream/25463; ENST00000483283/Downstream/6517;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/25444, chr7-CpG: 25/Downstream/38105
Upstream sequence
ctgaagaatcaagagagctgtatacctctattatttggaactatgagagtaataactgaagaaaaagccacttggggaatacagtccacttcgagaagca
Downstream sequence
gacttggggaatacagggaattgctcatttctgtcatgaacttttagccctctatgacttttaaaattataagaatgtattaactttgataaaaaGCTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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