Basic Information
VIS ID
TVIS44025834
Fusion event
HTLV-1-CHCHD3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
132610932/132926172 (Hg38)
End
132610932/132926172 (Hg38)
Orient
+
Location type
Intronic
Target gene
CHCHD3
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-6885-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-4439 ; hsa-mir-3977 ; hsa-mir-3136-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-2115-5p ; hsa-mir-6857-3p ; hsa-mir-4513 ; hsa-mir-6855-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-3938 ; hsa-mir-6800-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5581-3p ; hsa-mir-136-5p ; hsa-mir-4277 ; hsa-mir-584-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-148a-5p
Nearest miRNA
hsa-mir-10525/Upstream/2048633; hsa-mir-10399/Downstream/108688;
Nearest TSS
ENST00000635602/Upstream/95479; ENST00000481074/Downstream/125890;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/348404, chr7-CpG: 54/Downstream/155577
Upstream sequence
ACCATGGCAAGCCACTACGGAGTTTCTTGCATAGGAATCAGATACACCATTCCAGAGGCAATGTGGAACACAGAGGCAAGTAGACTAGTTGGGATATGCT
Downstream sequence
TGAAGCAGTACAGGCCAAATGAAGGCCAGAACAATGTCCAAGACAGCAAGTTTGGAATCCCAACTTATAAGTTACTGGTATCAGTAGAGTTTGGAAAGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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