Basic Information
VIS ID
TVIS44025856
Fusion event
HTLV-1-CNTNAP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q35
Reference genome
GRCh37/hg19
Start
146638373/146941281 (Hg38)
End
146638373/146941281 (Hg38)
Orient
+
Location type
Intronic
Target gene
CNTNAP2
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-99b-5p ; hsa-mir-4444 ; hsa-mir-6079 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-4428 ; hsa-mir-571 ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-mir-10399/Upstream/3558481; hsa-mir-153-2/Downstream/436736;
Nearest TSS
ENST00000635602/Upstream/25434; ENST00000637654/Downstream/21611;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/824289, chr7-CpG: 33/Downstream/1398121
Nearest cancer related gene
CNTNAP2(TSG, No orient, 0)
Upstream sequence
ttcttcttctcttactgtcttctttgtggtgattttctctagtggtacaattattttgttgctttttatttttagtgtatcaaagttatttgctttgtga
Downstream sequence
ttatcatgaagcttgcaaaagtcatcttacagttataacaggatattttaagcaaaagcaacttatctttgatcacaaaaaagcaactctacactttaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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