Basic Information
VIS ID
TVIS44025864
Fusion event
HTLV-1-CHPF2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
150931133/151234047 (Hg38)
End
150931133/151234047 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA7I
Target gene
CHPF2
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-98-5p ; hsa-mir-671-3p ; hsa-mir-766-3p ; hsa-mir-671-5p ; hsa-mir-193b-3p ; hsa-mir-339-5p ; hsa-mir-125b-5p ; hsa-mir-10b-5p
Nearest miRNA
hsa-mir-10399/Upstream/3855926; hsa-mir-153-2/Downstream/4374;
Nearest TSS
ENST00000635602/Upstream/1548; ENST00000465601/Downstream/1404;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/982, chr7-CpG: 19/Downstream/3516
Upstream sequence
CCCATCAATCCATTGATCCTTGAGGCTGTGCCCCTGGGGCACCCACCTGGCAGGGCCTACCACCATGCGACTGAGCTCCCTGTTGGCTCTGCTGCGGCCA
Downstream sequence
GCGCTTCCCCTCATCTTAGGGCTGTCTCTGGGGTGCAGCCTGAGCCTCCTGCGGGTTTCCTGGATCCAGGGGGAGGGAGAAGATCCCTGTGTCGAGGCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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