Basic Information
VIS ID
TVIS44025904
Fusion event
HTLV-1-GLI3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
42136377/42096778 (Hg38)
End
42136377/42096778 (Hg38)
Orient
-
Location type
Intronic
Target gene
GLI3
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-148b-3p ; hsa-mir-93-5p ; hsa-mir-200c-3p ; hsa-mir-378a-3p ; hsa-mir-506-3p ; hsa-mir-133b
Nearest miRNA
hsa-mir-1183/Upstream/5177346; hsa-mir-10399/Downstream/1054117;
Nearest TSS
ENST00000635602/Upstream/118856; ENST00000432845/Downstream/55642;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/130255, chr7-CpG: 163/Downstream/139626
Nearest cancer related gene
GLI3(OG, No orient, 0)
Upstream sequence
CTGCCTGGAGAGGGGGAAGGAAGAGATTCCAGAAGCCAGGTCAGAGCATGGAGAGTAAGCAGCAAGGGCCCAGAGAACTCTGCCATGGAAATCAGCCATG
Downstream sequence
AAACCAGACTCCAGCCACAGAGCTCCAAGGGCCTGGTGCCATCAAAGATAGGTTATCTCAAAAGACTGTTGCCTAAAAGTTGGATGTGATTGTGAGGGTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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