Basic Information
VIS ID
TVIS44025908
Fusion event
HTLV-1-NUDCD3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
44442250/44402651 (Hg38)
End
44442250/44402651 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
NUDCD3
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-324-3p ; hsa-mir-149-5p ; hsa-mir-92a-3p ; hsa-mir-1225-3p ; hsa-mir-5695 ; hsa-mir-3943 ; hsa-mir-6888-3p ; hsa-mir-3120-5p ; hsa-mir-371a-5p ; hsa-mir-3613-3p ; hsa-mir-3664-5p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-3662 ; hsa-mir-1251-3p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-28-5p ; hsa-mir-3139 ; hsa-mir-4487 ; hsa-mir-6128 ; hsa-mir-6505-5p ; hsa-mir-6516-5p ; hsa-mir-708-5p
Nearest miRNA
hsa-mir-1183/Upstream/291739; hsa-mir-10399/Downstream/479097;
Nearest TSS
ENST00000635602/Upstream/10143; ENST00000419661/Downstream/138;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/76933, chr7-CpG: 73/Downstream/87460
Upstream sequence
GCTATGGGCTCAGAGACCAGTGACTAAGGCTTTGGGCTTCTGCATGAAGTATCTAAAAAGTGCAACCGGACCACACACGGGGTTGCTCACCAAGAGCTCC
Downstream sequence
TCGCTCAGAGGGAACCAACTTGAGAGCATCGTGACCTGCTCCATGATCTGCACTGAGTTCACCCAACGGAAGGCAGGAGAGTCAAGGCCAGTGTTTTAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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