Basic Information
VIS ID
TVIS44025912
Fusion event
HTLV-1-ADCY1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
45638549/45598950 (Hg38)
End
45638549/45598950 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADCY1
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-331-3p ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-212-3p
Nearest miRNA
hsa-mir-1183/Upstream/717150; hsa-mir-10399/Downstream/11356835;
Nearest TSS
ENST00000635602/Upstream/24065; ENST00000646653/Downstream/49759;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/23045, chr7-CpG: 33/Downstream/127964
Upstream sequence
GGACGGAGCTCGGATTCCCACATCTCACAAAGGCCTGTCACGTGGACGGCAGGAAAAGCCTCTTTCTCAGTCTTGTTTTCATTAGTGGTTTGGCTTCTTG
Downstream sequence
GTGCCGAAGTGGATTGGGTGGGCGTCAGGTGGATGCTTGGTCCCTGCCCTGCTGCTGTTTCATGCACCAGGTTCTAGGAGCGAGGGGCAGGGCATGCTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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