Basic Information
VIS ID
TVIS44025926
Fusion event
HTLV-1-VOPP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
55532711/55465018 (Hg38)
End
55532711/55465018 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
VOPP1
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-320b ; hsa-mir-877-3p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-15b-5p ; hsa-mir-431-5p ; hsa-mir-5581-3p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-1343-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-374b-3p ; hsa-mir-424-5p ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-4690-3p ; hsa-mir-497-5p ; hsa-mir-503-5p ; hsa-mir-5685 ; hsa-mir-646 ; hsa-mir-6783-3p ; hsa-mir-6838-5p ; hsa-mir-938
Nearest miRNA
hsa-mir-1183/Upstream/10583218; hsa-mir-10399/Downstream/1490767;
Nearest TSS
ENST00000635602/Upstream/36962; ENST00000454777/Downstream/51059;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/15462, chr7-CpG: 144/Downstream/106566
Nearby gene
VOPP1(-5590) ;
Upstream sequence
ggggctctcctgtggctaggactgtaagagtcagtgtggcaatgtagactgctgaagatctcttgcttaccttctctctgcactggggggtttctcctgg
Downstream sequence
ctccgagctgattgcagctggaccagctgctttgcttccctctccttccaagcctcagatgttccctgtcacttctctgatgaattccattgttctctta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate